Self-guided reconstruction for time-domain fluorescence molecular lifetime tomography
نویسندگان
چکیده
منابع مشابه
Comparison of frequency-domain and time-domain fluorescence lifetime tomography.
We compare frequency-and time-domain formulations of deep-tissue fluorescence imaging of turbid media. Simulations are used to show that time-domain fluorescence tomography, implemented via the asymptotic lifetime-based approach, offers a significantly better separability of multiple lifetime targets than a frequency-domain approach. We also demonstrate experimentally, using complex-shaped phan...
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The study of dual-modality technology which combines microcomputed tomography (micro-CT) and fluorescence molecular tomography (FMT) has become one of the main focuses in FMT. However, because of the diversity of the optical properties and irregular geometry for small animals, a reconstruction method that can effectively utilize the high-resolution structural information of micro-CT for tissue ...
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In this study, several key optimization steps are outlined for a non-contact, time-correlated single photon counting small animal optical tomography system, using simultaneous collection of both fluorescence and transmittance data. The system is presented for time-domain image reconstruction in vivo, illustrating the sensitivity from single photon counting and the calibration steps needed to ac...
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ژورنال
عنوان ژورنال: Journal of Biomedical Optics
سال: 2016
ISSN: 1083-3668
DOI: 10.1117/1.jbo.21.12.126012